11832445

Source:http://linkedlifedata.com/resource/pubmed/id/11832445

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001128, umls-concept:C0004763, umls-concept:C0332157, umls-concept:C0752312, umls-concept:C1515877, umls-concept:C1704259, umls-concept:C1705987, umls-concept:C1879547
pubmed:issue	2
pubmed:dateCreated	2002-2-8
pubmed:abstractText	To explore mechanisms whereby acid reflux might contribute to carcinogenesis in Barrett's esophagus (BE) we studied: (1) the effects of acid on the mitogen-activated protein kinase (MAPK) pathways, cell proliferation, and apoptosis in a Barrett's adenocarcinoma cell line (SEG-1); and (2) the ability of acid to activate the MAPK pathways in vivo in patients with BE.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/HL52591, http://linkedlifedata.com/resource/pubmed/grant/HL61897
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0374630
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Hydrochloric Acid, http://linkedlifedata.com/resource/pubmed/chemical/JNK Mitogen-Activated Protein..., http://linkedlifedata.com/resource/pubmed/chemical/MAP Kinase Kinase 4, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase..., http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases, http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	0016-5085
pubmed:author	pubmed-author:ShewmakeKennethK, pubmed-author:SouzaRhonda FRF, pubmed-author:SpechlerStuart JonSJ, pubmed-author:TeradaLance SLS
pubmed:issnType	Print
pubmed:volume	122
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	299-307
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:11832445-Adenocarcinoma, pubmed-meshheading:11832445-Apoptosis, pubmed-meshheading:11832445-Barrett Esophagus, pubmed-meshheading:11832445-Biopsy, pubmed-meshheading:11832445-Cell Count, pubmed-meshheading:11832445-Cell Division, pubmed-meshheading:11832445-Cell Survival, pubmed-meshheading:11832445-Enzyme Activation, pubmed-meshheading:11832445-Esophageal Neoplasms, pubmed-meshheading:11832445-Humans, pubmed-meshheading:11832445-Hydrochloric Acid, pubmed-meshheading:11832445-JNK Mitogen-Activated Protein Kinases, pubmed-meshheading:11832445-MAP Kinase Kinase 4, pubmed-meshheading:11832445-MAP Kinase Signaling System, pubmed-meshheading:11832445-Mitogen-Activated Protein Kinase Kinases, pubmed-meshheading:11832445-Mitogen-Activated Protein Kinases, pubmed-meshheading:11832445-Mucous Membrane, pubmed-meshheading:11832445-Tumor Cells, Cultured, pubmed-meshheading:11832445-p38 Mitogen-Activated Protein Kinases
pubmed:year	2002
pubmed:articleTitle	Acid exposure activates the mitogen-activated protein kinase pathways in Barrett's esophagus.
pubmed:affiliation	Department of Medicine, Dallas VA Medical Center and University of Texas-Southwestern Medical School, Dallas, Texas 75216, USA. rsouza@airmail.net
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't