|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0039082,
umls-concept:C0178719,
umls-concept:C0205266,
umls-concept:C0205390,
umls-concept:C0332120,
umls-concept:C0344432,
umls-concept:C0439661,
umls-concept:C0439851,
umls-concept:C0504053,
umls-concept:C1444748,
umls-concept:C1552596,
umls-concept:C1947931,
umls-concept:C2003851
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|
pubmed:issue |
23
|
|
pubmed:dateCreated |
2001-6-12
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|
pubmed:abstractText |
This study examined the role of phase 2 early afterdepolarization (EAD) in producing a trigger to initiate torsade de pointes (TdP) with QT prolongation induced by dl-sotalol and azimilide. The contribution of transmural dispersion of repolarization (TDR) to transmural propagation of EAD and the maintenance of TdP was also evaluated.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1524-4539
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:day |
12
|
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pubmed:volume |
103
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
2851-6
|
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11401944-Action Potentials,
pubmed-meshheading:11401944-Animals,
pubmed-meshheading:11401944-Anti-Arrhythmia Agents,
pubmed-meshheading:11401944-Dogs,
pubmed-meshheading:11401944-Dose-Response Relationship, Drug,
pubmed-meshheading:11401944-Electrocardiography,
pubmed-meshheading:11401944-Electrophysiologic Techniques, Cardiac,
pubmed-meshheading:11401944-Heart Conduction System,
pubmed-meshheading:11401944-Heart Ventricles,
pubmed-meshheading:11401944-Imidazoles,
pubmed-meshheading:11401944-Imidazolidines,
pubmed-meshheading:11401944-Long QT Syndrome,
pubmed-meshheading:11401944-Myocardial Contraction,
pubmed-meshheading:11401944-Piperazines,
pubmed-meshheading:11401944-Rabbits,
pubmed-meshheading:11401944-Sotalol,
pubmed-meshheading:11401944-Species Specificity,
pubmed-meshheading:11401944-Systole,
pubmed-meshheading:11401944-Tachycardia, Ventricular,
pubmed-meshheading:11401944-Ventricular Dysfunction, Left
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pubmed:year |
2001
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|
pubmed:articleTitle |
Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome : direct evidence from intracellular recordings in the intact left ventricular wall.
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pubmed:affiliation |
Main Line Health Heart Center, Wynnewood, PA, USA. yanganxin@cs.com
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
