Linked Life Data

11139135

Source:http://linkedlifedata.com/resource/pubmed/id/11139135

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2001-1-2
pubmed:abstractText
The F2 isoprostanes are a unique series of prostaglandinlike compounds formed in vivo from the free-radical-catalyzed peroxidation of arachidonic acid independent of the cyclooxygenase enzyme. The purpose of this review is to briefly summarize the status of our current knowledge regarding the isoprostanes. Novel aspects related to the biochemistry of isoprostane formation and methods by which these compounds are analyzed are discussed. The utility of measuring F2 isoprostanes as markers of lipid peroxidation in animal models of oxidant stress are then outlined. Finally, examples are provided in which quantification of isoprostanes have illuminated the role of oxidative injury in several human diseases.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0360-2532
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
377-85
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
The isoprostanes: their quantification as an index of oxidant stress status in vivo.
pubmed:affiliation
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6602, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't