rdf:type |
|
lifeskim:mentions |
umls-concept:C0006118,
umls-concept:C0017262,
umls-concept:C0033681,
umls-concept:C0058454,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0332290,
umls-concept:C1514562,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221,
umls-concept:C2911684
|
pubmed:issue |
6
|
pubmed:dateCreated |
2000-12-20
|
pubmed:abstractText |
Few molecular targets are both consistently and selectively expressed in a majority of central nervous system (CNS) neoplasms. Receptor tyrosine kinases have been implicated in brain tumor oncogenesis. We previously isolated one such receptor, discoidin domain receptor-1 (DDR1), from high-grade pediatric brain tumors. Here, we analyze the cellular origin and distribution of DDR1 expression in human brain tumors and its expression in tumor cells relative to surrounding brain.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/FAM107A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Mitogen,
http://linkedlifedata.com/resource/pubmed/chemical/discoidin receptor
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pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0148-396X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1400-9
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pubmed:dateRevised |
2010-9-22
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pubmed:meshHeading |
pubmed-meshheading:11126911-Adolescent,
pubmed-meshheading:11126911-Adult,
pubmed-meshheading:11126911-Aged,
pubmed-meshheading:11126911-Animals,
pubmed-meshheading:11126911-Brain,
pubmed-meshheading:11126911-Brain Neoplasms,
pubmed-meshheading:11126911-Cerebral Ventricle Neoplasms,
pubmed-meshheading:11126911-Child,
pubmed-meshheading:11126911-Child, Preschool,
pubmed-meshheading:11126911-Embryo, Mammalian,
pubmed-meshheading:11126911-Female,
pubmed-meshheading:11126911-Genes, Tumor Suppressor,
pubmed-meshheading:11126911-Glioma,
pubmed-meshheading:11126911-Humans,
pubmed-meshheading:11126911-Male,
pubmed-meshheading:11126911-Mice,
pubmed-meshheading:11126911-Middle Aged,
pubmed-meshheading:11126911-Neoplasm Transplantation,
pubmed-meshheading:11126911-Nuclear Proteins,
pubmed-meshheading:11126911-Protein-Tyrosine Kinases,
pubmed-meshheading:11126911-Proteins,
pubmed-meshheading:11126911-RNA, Messenger,
pubmed-meshheading:11126911-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:11126911-Receptors, Mitogen,
pubmed-meshheading:11126911-Tumor Cells, Cultured
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pubmed:year |
2000
|
pubmed:articleTitle |
Consistent and selective expression of the discoidin domain receptor-1 tyrosine kinase in human brain tumors.
|
pubmed:affiliation |
Division of Pediatric Neurosurgery, New York University School of Medicine, New York 10016, USA. howard.weiner@med.nyu.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|