Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-12-20
pubmed:abstractText
Few molecular targets are both consistently and selectively expressed in a majority of central nervous system (CNS) neoplasms. Receptor tyrosine kinases have been implicated in brain tumor oncogenesis. We previously isolated one such receptor, discoidin domain receptor-1 (DDR1), from high-grade pediatric brain tumors. Here, we analyze the cellular origin and distribution of DDR1 expression in human brain tumors and its expression in tumor cells relative to surrounding brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0148-396X
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1400-9
pubmed:dateRevised
2010-9-22
pubmed:meshHeading
pubmed-meshheading:11126911-Adolescent, pubmed-meshheading:11126911-Adult, pubmed-meshheading:11126911-Aged, pubmed-meshheading:11126911-Animals, pubmed-meshheading:11126911-Brain, pubmed-meshheading:11126911-Brain Neoplasms, pubmed-meshheading:11126911-Cerebral Ventricle Neoplasms, pubmed-meshheading:11126911-Child, pubmed-meshheading:11126911-Child, Preschool, pubmed-meshheading:11126911-Embryo, Mammalian, pubmed-meshheading:11126911-Female, pubmed-meshheading:11126911-Genes, Tumor Suppressor, pubmed-meshheading:11126911-Glioma, pubmed-meshheading:11126911-Humans, pubmed-meshheading:11126911-Male, pubmed-meshheading:11126911-Mice, pubmed-meshheading:11126911-Middle Aged, pubmed-meshheading:11126911-Neoplasm Transplantation, pubmed-meshheading:11126911-Nuclear Proteins, pubmed-meshheading:11126911-Protein-Tyrosine Kinases, pubmed-meshheading:11126911-Proteins, pubmed-meshheading:11126911-RNA, Messenger, pubmed-meshheading:11126911-Receptor Protein-Tyrosine Kinases, pubmed-meshheading:11126911-Receptors, Mitogen, pubmed-meshheading:11126911-Tumor Cells, Cultured
pubmed:year
2000
pubmed:articleTitle
Consistent and selective expression of the discoidin domain receptor-1 tyrosine kinase in human brain tumors.
pubmed:affiliation
Division of Pediatric Neurosurgery, New York University School of Medicine, New York 10016, USA. howard.weiner@med.nyu.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't