rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1979-8-29
|
pubmed:abstractText |
Thirty-two patients with a diagnosis of primary inflammatory breast carcinoma were treated with combination chemoimmunotherapy consisting of 5-fluorouracil, doxorubicin hydrochloride (Adriamycin), and cyclophosphamide (FAC) plus BCG followed by radiation therapy. This group of patients was compared to a group of 32 consecutive historical controls treated with radiation therapy alone. The estimated mean disease-free interval for the FAC-BCG group was 16 months, compared to 9 months for the radiation therapy alone group (P less than 0.01). The estimated median survival for the FAC-BCG treated group was 24 months, compared to 18 months for the radiation therapy alone group (P = less than 0.03). The combined modality approach consisting of chemoimmunotherapy and radiation therapy significantly improved the disease-free interval and survival of patients with inflammatory breast carcinoma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0022-4790
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
325-32
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:109703-Adult,
pubmed-meshheading:109703-Aged,
pubmed-meshheading:109703-Antineoplastic Agents,
pubmed-meshheading:109703-BCG Vaccine,
pubmed-meshheading:109703-Breast Neoplasms,
pubmed-meshheading:109703-Cyclophosphamide,
pubmed-meshheading:109703-Doxorubicin,
pubmed-meshheading:109703-Drug Therapy, Combination,
pubmed-meshheading:109703-Female,
pubmed-meshheading:109703-Fluorouracil,
pubmed-meshheading:109703-Humans,
pubmed-meshheading:109703-Middle Aged,
pubmed-meshheading:109703-Radiotherapy, High-Energy,
pubmed-meshheading:109703-Recurrence,
pubmed-meshheading:109703-Remission, Spontaneous,
pubmed-meshheading:109703-Time Factors
|
pubmed:year |
1979
|
pubmed:articleTitle |
Combined chemoimmunotherapy and radiation therapy of inflammatory breast carcinoma.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
|