| pubmed-article:10712498 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10712498 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:10712498 | lifeskim:mentions | umls-concept:C0029246 | lld:lifeskim |
| pubmed-article:10712498 | lifeskim:mentions | umls-concept:C0030193 | lld:lifeskim |
| pubmed-article:10712498 | lifeskim:mentions | umls-concept:C0037658 | lld:lifeskim |
| pubmed-article:10712498 | lifeskim:mentions | umls-concept:C0702221 | lld:lifeskim |
| pubmed-article:10712498 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:10712498 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:10712498 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10712498 | pubmed:dateCreated | 2000-4-11 | lld:pubmed |
| pubmed-article:10712498 | pubmed:abstractText | Processing of tactile stimuli within somatosensory cortices has been shown to be complex and hierarchically organized. However, the precise organization of nociceptive processing within these cortices has remained largely unknown. We used whole-head magnetoencephalography to directly compare cortical responses to stimulation of tactile and nociceptive afferents of the dorsum of the hand in humans. Within the primary somatosensory cortex (SI), nociceptive stimuli activated a single source whereas tactile stimuli activated two sequentially peaking sources. Along the postcentral gyrus, the nociceptive SI source was located 10 mm more medially than the early tactile SI response arising from cytoarchitectonical area 3b and corresponded spatially to the later tactile SI response. Considering a mediolateral location difference between the hand representations of cytoarchitectonical areas 3b and 1, the present results suggest generation of the single nociceptive response in area 1, whereas tactile stimuli activate sequentially peaking sources in areas 3b and 1. Thus nociceptive processing apparently does not share the complex and hierarchical organization of tactile processing subserving elaborated sensory capacities. This difference in the organization of both modalities may reflect that pain perception rather requires reactions to and avoidance of harmful stimuli than sophisticated sensory capacities. | lld:pubmed |
| pubmed-article:10712498 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10712498 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10712498 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10712498 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10712498 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:10712498 | pubmed:issn | 0022-3077 | lld:pubmed |
| pubmed-article:10712498 | pubmed:author | pubmed-author:SchmittHH | lld:pubmed |
| pubmed-article:10712498 | pubmed:author | pubmed-author:FreundH JHJ | lld:pubmed |
| pubmed-article:10712498 | pubmed:author | pubmed-author:SchnitzlerAA | lld:pubmed |
| pubmed-article:10712498 | pubmed:author | pubmed-author:PlonerMM | lld:pubmed |
| pubmed-article:10712498 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10712498 | pubmed:volume | 83 | lld:pubmed |
| pubmed-article:10712498 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10712498 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10712498 | pubmed:pagination | 1770-6 | lld:pubmed |
| pubmed-article:10712498 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:meshHeading | pubmed-meshheading:10712498... | lld:pubmed |
| pubmed-article:10712498 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10712498 | pubmed:articleTitle | Differential organization of touch and pain in human primary somatosensory cortex. | lld:pubmed |
| pubmed-article:10712498 | pubmed:affiliation | Department of Neurology, Heinrich-Heine-University, D-40225 Düsseldorf, Germany. | lld:pubmed |
| pubmed-article:10712498 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10712498 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:10712498 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10712498 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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