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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2000-2-29
pubmed:abstractText
In order to identify overall and site-specific nosocomial infection (NI) rates in patients receiving neurosurgical intensive care therapy, a prospective study was started in February 1997 in the eight-bed neurosurgical ICU of the University Hospital of Freiburg, Germany. Case records were reviewed twice a week, all microbiology reports were reviewed and ward staff was consulted. NI were defined according to the CDC-criteria and were categorised into specific infection sites. Within 20 months, 545 patients with a total of 5,117 patient days were investigated (mean length of stay: 9.4 days). 113 NI were identified in 90 patients (72 pts. with one, 13 with two and 5 with three infections, respectively). A moderate to high overall incidence (20.7/100 pts.) and a moderate incidence density (22.1/1,000 patient days) of NI in the neurosurgical ICU could be documented; these figures are well within the range of published data. Site specific incidence rates and incidence densities were: 1 bloodstream infection per 100 patients (0.9 central line-associated BSIs per 1,000 central line-days), 9 pneumonias per 100 patients (15.1 ventilator-associated pneumonias per 1,000 ventilator-days), 7.3 urinary tract infections per 100 patients (8.5 urinary catheter-associated UTIs per 1,000 urinary catheter-days). Additionally, 1.1 cases of meningitis, 0.7 brain abscesses/ventriculitis, and 1.7 other infections (surgical site infection, bronchitis, catheter related local infection, diarrhoea) were documented per 100 patients, respectively. 14.6% of isolated pathogens were E. coli, 10.2% enterococci, 9.6% S. aureus, 6.4% CNS, 6.4% Klebsiella spp., 5% Enterobacter spp. and 5% Pseudomonas spp. In 11 cases of NI no pathogen could be isolated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-6268
pubmed:author
pubmed:issnType
Print
pubmed:volume
141
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1303-8
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed-meshheading:10672301-Adolescent, pubmed-meshheading:10672301-Adult, pubmed-meshheading:10672301-Aged, pubmed-meshheading:10672301-Aged, 80 and over, pubmed-meshheading:10672301-Bacteriological Techniques, pubmed-meshheading:10672301-Central Nervous System Diseases, pubmed-meshheading:10672301-Child, pubmed-meshheading:10672301-Cross Infection, pubmed-meshheading:10672301-Cross-Sectional Studies, pubmed-meshheading:10672301-Female, pubmed-meshheading:10672301-Germany, pubmed-meshheading:10672301-Humans, pubmed-meshheading:10672301-Incidence, pubmed-meshheading:10672301-Intensive Care Units, pubmed-meshheading:10672301-Male, pubmed-meshheading:10672301-Middle Aged, pubmed-meshheading:10672301-Population Surveillance, pubmed-meshheading:10672301-Retrospective Studies, pubmed-meshheading:10672301-Surgical Wound Infection
pubmed:year
1999
pubmed:articleTitle
Nosocomial infections in a neurosurgery intensive care unit.
pubmed:affiliation
Institute of Environmental Medicine and Hospital Epidemiology, University Hospital Freiburg, Germany.
pubmed:publicationType
Journal Article