pubmed-article:10527644 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10527644 | lifeskim:mentions | umls-concept:C0026549 | lld:lifeskim |
pubmed-article:10527644 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:10527644 | lifeskim:mentions | umls-concept:C0006405 | lld:lifeskim |
pubmed-article:10527644 | lifeskim:mentions | umls-concept:C1510470 | lld:lifeskim |
pubmed-article:10527644 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:10527644 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:10527644 | pubmed:dateCreated | 1999-12-7 | lld:pubmed |
pubmed-article:10527644 | pubmed:abstractText | The effects of buprenorphine (0.0125-0.2 mg kg(-1)) on the locomotor activity of rats were determined 1-2 months after ceasing a chronic treatment with morphine (20 mg kg(-1)for 28 days). In control animals buprenorphine exhibited both depressive and stimulatory actions, as repeatedly described for morphine. In post-dependent animals buprenorphine showed a depressive effect similar to that observed in naive ones. On the contrary, a persistent sensitization to the excitatory effect was observed; the degree of cross-sensitization was similar to that of morphine itself (20 mg kg(-1)). The results are discussed in terms of persistent changes in the locomotor response to opioids, possibly correlated to both drug craving and relapse. | lld:pubmed |
pubmed-article:10527644 | pubmed:language | eng | lld:pubmed |
pubmed-article:10527644 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10527644 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10527644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10527644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10527644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10527644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10527644 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10527644 | pubmed:month | Oct | lld:pubmed |
pubmed-article:10527644 | pubmed:issn | 1043-6618 | lld:pubmed |
pubmed-article:10527644 | pubmed:author | pubmed-author:GaiardiMM | lld:pubmed |
pubmed-article:10527644 | pubmed:author | pubmed-author:BartolettiMM | lld:pubmed |
pubmed-article:10527644 | pubmed:author | pubmed-author:GubelliniCC | lld:pubmed |
pubmed-article:10527644 | pubmed:copyrightInfo | Copyright 1999 Academic Press. | lld:pubmed |
pubmed-article:10527644 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10527644 | pubmed:volume | 40 | lld:pubmed |
pubmed-article:10527644 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10527644 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10527644 | pubmed:pagination | 327-32 | lld:pubmed |
pubmed-article:10527644 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
pubmed-article:10527644 | pubmed:meshHeading | pubmed-meshheading:10527644... | lld:pubmed |
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pubmed-article:10527644 | pubmed:meshHeading | pubmed-meshheading:10527644... | lld:pubmed |
pubmed-article:10527644 | pubmed:year | 1999 | lld:pubmed |
pubmed-article:10527644 | pubmed:articleTitle | Effects of buprenorphine on motility in morphine post-dependent rats. | lld:pubmed |
pubmed-article:10527644 | pubmed:affiliation | Department of Pharmacology, University of Bologna, Via Irnerio 48, Bologna, I-40126, Italy. | lld:pubmed |
pubmed-article:10527644 | pubmed:publicationType | Journal Article | lld:pubmed |