| pubmed-article:10218816 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0028165 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0072662 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0244119 | lld:lifeskim |
| pubmed-article:10218816 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:10218816 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:10218816 | pubmed:dateCreated | 1999-7-19 | lld:pubmed |
| pubmed-article:10218816 | pubmed:abstractText | The design and synthesis of novel benzoic acid mustard (BAM) derivatives of distamycin A bearing one or more pyrazole rings replacing the pyrrole rings of the latter are described. In vitro and in vivo activities against L1210 leukemia are reported and discussed. Some of these compounds show an activity profile comparable to tallimustine 1. All the compounds bearing the pyrazole ring close to the BAM moiety show reduced cytotoxicity in comparison to derivatives characterized by the BAM linked to a pyrrole: the same effect has not been observed when occurring at the amidine terminus of the oligopeptidic frame. | lld:pubmed |
| pubmed-article:10218816 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10218816 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10218816 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10218816 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10218816 | pubmed:issn | 0968-0896 | lld:pubmed |
| pubmed-article:10218816 | pubmed:author | pubmed-author:BaraldiP GPG | lld:pubmed |
| pubmed-article:10218816 | pubmed:author | pubmed-author:RomagnoliRR | lld:pubmed |
| pubmed-article:10218816 | pubmed:author | pubmed-author:CozziPP | lld:pubmed |
| pubmed-article:10218816 | pubmed:author | pubmed-author:MongelliNN | lld:pubmed |
| pubmed-article:10218816 | pubmed:author | pubmed-author:SpallutoGG | lld:pubmed |
| pubmed-article:10218816 | pubmed:author | pubmed-author:GeroniCC | lld:pubmed |
| pubmed-article:10218816 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10218816 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:10218816 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10218816 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10218816 | pubmed:pagination | 251-62 | lld:pubmed |
| pubmed-article:10218816 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
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| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
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| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
| pubmed-article:10218816 | pubmed:meshHeading | pubmed-meshheading:10218816... | lld:pubmed |
| pubmed-article:10218816 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10218816 | pubmed:articleTitle | Novel benzoyl nitrogen mustard derivatives of pyrazole analogues of distamycin A: synthesis and antileukemic activity. | lld:pubmed |
| pubmed-article:10218816 | pubmed:affiliation | Dipartimento di Scienze Farmaceutiche, Università di Ferrara, Italy. pgb@ifeuniv.unife.it | lld:pubmed |
| pubmed-article:10218816 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10218816 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10218816 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10218816 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10218816 | lld:pubmed |
