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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1999-3-10
|
| pubmed:abstractText |
The authors studied the effect of ligation of the femoral and saphenous veins on the evolution of lipase injection-induced subcutaneous fibrosis and inflammation in the rats' hindlimbs. The superficial muscular fascia was thickened and the number of veins was increased 3 days and 3 weeks after vein ligation; both abnormalities disappeared 6 weeks postoperatively. Vein ligation did not quantitatively affect fascial thickening or fibrosing panniculitis in hindlimbs injected with lipase 6 weeks prior to sacrifice. The results contradict the proposition that lipase-induced injury of rats' subcutaneous tissues compromised by venous stasis may lead to a persistent chronic inflammation and fibrosis of the subcutaneous-fascial complex duplicating lipodermatosclerosis in man.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0923-1811
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
19
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
9-16
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9890369-Acute Disease,
pubmed-meshheading:9890369-Adipose Tissue,
pubmed-meshheading:9890369-Animals,
pubmed-meshheading:9890369-Disease Models, Animal,
pubmed-meshheading:9890369-Female,
pubmed-meshheading:9890369-Femoral Vein,
pubmed-meshheading:9890369-Hindlimb,
pubmed-meshheading:9890369-Ligation,
pubmed-meshheading:9890369-Lipase,
pubmed-meshheading:9890369-Male,
pubmed-meshheading:9890369-Panniculitis,
pubmed-meshheading:9890369-Rats,
pubmed-meshheading:9890369-Rats, Sprague-Dawley,
pubmed-meshheading:9890369-Saphenous Vein,
pubmed-meshheading:9890369-Skin,
pubmed-meshheading:9890369-Vascular Diseases,
pubmed-meshheading:9890369-Veins,
pubmed-meshheading:9890369-Venous Insufficiency
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Acute lipase-induced panniculitis in rats with ligated veins of the hindlimb: a contribution to the role of acute panniculitis as a precursor of lipodermatosclerosis of venous disease.
|
| pubmed:affiliation |
Department of Internal Medicine A, Bnai-Zion Medical Center and The Bruce Rapapport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
|
| pubmed:publicationType |
Journal Article
|