Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-2-3
pubmed:abstractText
Malignant melanoma is an antigenic tumor recognized by specific lymphocytes. Several melanoma-associated antigens have been shown to cause tumor rejection in vitro. Escape from immunosurveillance by melanoma cells is the result of several mechanisms such as total loss or decreased expression of HLA antigens, alterations in the expression of tumor-associated antigens or deficiencies in the antigen-processing machinery. Additional important features include the influence of endogenous and exogenous cytokines such as interferons or interleukins and expression of adhesion molecules or co-stimulatory molecules. All these factor have to be considered for the development of new immunoregulatory treatment modalities against advanced melanoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1107-3756
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-57
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Immune escape mechanisms in malignant melanoma.
pubmed:affiliation
Department of Dermatology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
pubmed:publicationType
Journal Article, Review