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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1998-11-25
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pubmed:abstractText |
Allogeneic bone marrow transplantation has proven effective for inducing specific tolerance to subsequent solid organ allografts, although the clinical applicability of this approach is limited by the morbidity and mortality associated with this procedure. As an alternative, we are investigating the transfer of allogeneic MHC class II genes into recipient bone marrow cells (BMC), using the miniature swine as a model.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1081-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9808495-Animals,
pubmed-meshheading:9808495-Bone Marrow Cells,
pubmed-meshheading:9808495-Bone Marrow Transplantation,
pubmed-meshheading:9808495-Gene Deletion,
pubmed-meshheading:9808495-Gene Transfer Techniques,
pubmed-meshheading:9808495-Genetic Vectors,
pubmed-meshheading:9808495-Germ-Free Life,
pubmed-meshheading:9808495-HLA-DR Antigens,
pubmed-meshheading:9808495-Immune Tolerance,
pubmed-meshheading:9808495-Mice,
pubmed-meshheading:9808495-Mice, Inbred C57BL,
pubmed-meshheading:9808495-Receptors, Antigen, T-Cell, alpha-beta,
pubmed-meshheading:9808495-Retroviridae,
pubmed-meshheading:9808495-Stem Cells,
pubmed-meshheading:9808495-Superantigens,
pubmed-meshheading:9808495-Swine,
pubmed-meshheading:9808495-Swine, Miniature,
pubmed-meshheading:9808495-T-Lymphocytes
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pubmed:year |
1998
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pubmed:articleTitle |
Transfer of porcine MHC DRalpha into IEalpha-deficient murine bone marrow results in reduced IE-restricted Vbeta usage.
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pubmed:affiliation |
Transplantation Biology Research Center, Massachusetts General Hospital/Harvard Medical School, Boston 02129, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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