Linked Life Data

970737

Source:http://linkedlifedata.com/resource/pubmed/id/970737

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1976-11-21
pubmed:abstractText
The purpose of the present study was to obtain further information regarding the chemical nature and cell of origin of the surface secretion of the bronchiole using radioautography after the injection of labeled leucine, glucosamine, galactose. Rat lungs were perfused with mammalian Ringer's solution with added albumin. A 10-min pulse of L-leucine labeled with hydrogen-3 was administered, followed by perfusion with nonradioactive solution for 15 min to 4 hours. Similar studies were performed with [3H] glucosamine and [3H] galactose. Heavy labeling of the Clara cells of bronchioles was obtained after injection of [3H] L-leucine. Labeling of alveolar wall cells was also obtained. Labeling of the surface of the bronchiole was much heavier than the labeling of the surface of the alveoli. No specific labeling of bronchiolar cells was obtained with [3H] glucosamine and [3H] galactose. The results provide added evidence for the protein nature of the surface layer of the bronchiole and for the Clara cell as its cell of origin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-73
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Study of the surface secretion of the bronchiole using radioautography.
pubmed:publicationType
Journal Article