rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1998-8-28
|
pubmed:abstractText |
Recently five somatostatin receptor subtypes (SSTRs) were cloned, allowing the development of highly specific agonists to these SSTRs. Previous studies have shown a species specificity phenomenon with respect to the inhibition of insulin secretion by these selective agonists. This study was undertaken to determine which SSTR (2 or 5) is responsible for the inhibitory effect of somatostatin on glucose-stimulated mouse insulin secretion.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0039-6060
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
124
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
254-8; discussion 258-9
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:9706146-Animals,
pubmed-meshheading:9706146-Blotting, Southern,
pubmed-meshheading:9706146-Dose-Response Relationship, Drug,
pubmed-meshheading:9706146-Glucose,
pubmed-meshheading:9706146-Insulin,
pubmed-meshheading:9706146-Islets of Langerhans,
pubmed-meshheading:9706146-Male,
pubmed-meshheading:9706146-Mice,
pubmed-meshheading:9706146-Mice, Inbred Strains,
pubmed-meshheading:9706146-Organ Culture Techniques,
pubmed-meshheading:9706146-Polymerase Chain Reaction,
pubmed-meshheading:9706146-RNA, Messenger,
pubmed-meshheading:9706146-Receptors, Somatostatin
|
pubmed:year |
1998
|
pubmed:articleTitle |
Insulin secretion is inhibited by subtype five somatostatin receptor in the mouse.
|
pubmed:affiliation |
Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|