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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-8-20
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pubmed:abstractText |
Dynorphin A(1-13) is a fragment of the endogenous opioid neuropeptide dynorphin A. Previous research suggested that intravenously administered dynorphin A(1-13) has the ability to modulate morphine-induced analgesia. We designed this study to characterize the disposition of intravenous dynorphin immunoreactivity in humans and to determine whether concomitant long-term opioid therapy influenced the pharmacokinetics or side-effects profile of dynorphin A(1-13).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0009-9236
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-38
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9695716-Adult,
pubmed-meshheading:9695716-Aged,
pubmed-meshheading:9695716-Analgesics, Opioid,
pubmed-meshheading:9695716-Drug Interactions,
pubmed-meshheading:9695716-Dynorphins,
pubmed-meshheading:9695716-Humans,
pubmed-meshheading:9695716-Immunoassay,
pubmed-meshheading:9695716-Infusions, Intravenous,
pubmed-meshheading:9695716-Male,
pubmed-meshheading:9695716-Middle Aged,
pubmed-meshheading:9695716-Peptide Fragments
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pubmed:year |
1998
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pubmed:articleTitle |
Pharmacokinetics of intravenous dynorphin A(1-13) in opioid-naive and opioid-treated human volunteers.
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pubmed:affiliation |
Departmento de Anestesiologia, Ciutat Sanitaria i Universitaria de Bellvitge, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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