Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1998-9-29
pubmed:abstractText
The knowledge progressively accumulated on the relation between changes in autonomic activity and cardiac mortality, particularly in the setting of acute myocardial ischaemia, has turned during the last decade toward the potential prognostic value of markers of autonomic activity. Two of these markers, heart rate variability and baroreflex sensitivity, have gained progressive popularity. This chapter reviews some of the experimental observations that were instrumental for the novel clinical approach to post-myocardial infarction risk stratification based on the use of autonomic markers as risk stratifiers. It then focuses on clinical studies with special attention for a very recent multicentre prospective study (ATRAMI) carried out in almost 1300 post-myocardial infarction patients and aimed at the evaluation of the prognostic value of both heart rate variability and baroreflex sensitivity. Finally, some pathophysiological considerations are added to clarify the legitimacy, or lack of it, of the terminology currently used in clinical studies based on autonomic markers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0195-668X
pubmed:author
pubmed:issnType
Print
pubmed:volume
19 Suppl F
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
F72-80
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
The autonomic nervous system and sudden death.
pubmed:affiliation
Cattedra di Cardiologia, Università degli Studi di Pavia, Italy.
pubmed:publicationType
Journal Article, Review