| pubmed-article:9600344 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9600344 | lifeskim:mentions | umls-concept:C0330499 | lld:lifeskim |
| pubmed-article:9600344 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:9600344 | lifeskim:mentions | umls-concept:C0442805 | lld:lifeskim |
| pubmed-article:9600344 | lifeskim:mentions | umls-concept:C0607203 | lld:lifeskim |
| pubmed-article:9600344 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9600344 | pubmed:dateCreated | 1998-6-4 | lld:pubmed |
| pubmed-article:9600344 | pubmed:abstractText | The putative anticarcinogenic activity of Brassica vegetables has been associated with the presence of certain glucosinolates. 4-Methylsulphinylbutyl isothiocyanate (sulphoraphane), derived from the corresponding glucosinolate found in broccoli, has previously been identified as a potent inducer of the anticarcinogenic marker enzyme quinone reductase [NADP(H):quinone-acceptor oxidoreductase] in murine hepatoma Hepa 1c1c7 cells. We have therefore produced a broccoli hybrid with increased levels of this anticarcinogenic glucosinolate and tested the ability of extracts to induce quinone reductase. A 10-fold increase in the level of 4-methylsulphinylbutyl glucosinolate was obtained by crossing broccoli cultivars with selected wild taxa of the Brassica oleracea (chromosome number, n = 9) complex. Tissue from these hybrids exhibited a >100-fold increase in the ability to induce quinone reductase in Hepa 1c1c7 cells over broccoli cultivars, due to both an increase in 4-methylsulphinylbutyl glucosinolate content and increased percentage conversion to sulphoraphane. | lld:pubmed |
| pubmed-article:9600344 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9600344 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9600344 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9600344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9600344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9600344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9600344 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9600344 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9600344 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:9600344 | pubmed:issn | 0143-3334 | lld:pubmed |
| pubmed-article:9600344 | pubmed:author | pubmed-author:FaulknerKK | lld:pubmed |
| pubmed-article:9600344 | pubmed:author | pubmed-author:WilliamsonGG | lld:pubmed |
| pubmed-article:9600344 | pubmed:author | pubmed-author:MithenRR | lld:pubmed |
| pubmed-article:9600344 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9600344 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:9600344 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9600344 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9600344 | pubmed:pagination | 605-9 | lld:pubmed |
| pubmed-article:9600344 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:9600344 | pubmed:meshHeading | pubmed-meshheading:9600344-... | lld:pubmed |
| pubmed-article:9600344 | pubmed:meshHeading | pubmed-meshheading:9600344-... | lld:pubmed |
| pubmed-article:9600344 | pubmed:meshHeading | pubmed-meshheading:9600344-... | lld:pubmed |
| pubmed-article:9600344 | pubmed:meshHeading | pubmed-meshheading:9600344-... | lld:pubmed |
| pubmed-article:9600344 | pubmed:meshHeading | pubmed-meshheading:9600344-... | lld:pubmed |
| pubmed-article:9600344 | pubmed:meshHeading | pubmed-meshheading:9600344-... | lld:pubmed |
| pubmed-article:9600344 | pubmed:meshHeading | pubmed-meshheading:9600344-... | lld:pubmed |
| pubmed-article:9600344 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9600344 | pubmed:articleTitle | Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosinolate in broccoli. | lld:pubmed |
| pubmed-article:9600344 | pubmed:affiliation | John Innes Centre, Norwich Research Park, UK. | lld:pubmed |
| pubmed-article:9600344 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9600344 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9600344 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9600344 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9600344 | lld:pubmed |
