|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0014544,
umls-concept:C0017296,
umls-concept:C0019564,
umls-concept:C0040300,
umls-concept:C0079429,
umls-concept:C0086022,
umls-concept:C0086418,
umls-concept:C0439851,
umls-concept:C0442335,
umls-concept:C0449445,
umls-concept:C1517499,
umls-concept:C1552596,
umls-concept:C1564874,
umls-concept:C1705099,
umls-concept:C1947931
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1998-5-21
|
|
pubmed:abstractText |
Virus vectors capable of transferring genetic information into human cells provide hope for improved therapy in several neurological diseases, including epilepsy. We evaluated the ability of an adeno-associated virus (AAV) vector to transfer and cause expression of a lacZ marker gene in brain slices obtained from patients undergoing temporal lobectomy for control of medically intractable seizures.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0013-9580
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
38
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
759-66
|
|
pubmed:dateRevised |
2006-4-21
|
|
pubmed:meshHeading |
pubmed-meshheading:9579902-Dependovirus,
pubmed-meshheading:9579902-Epilepsy,
pubmed-meshheading:9579902-Escherichia coli,
pubmed-meshheading:9579902-Gene Therapy,
pubmed-meshheading:9579902-Gene Transfer Techniques,
pubmed-meshheading:9579902-Genetic Vectors,
pubmed-meshheading:9579902-Hippocampus,
pubmed-meshheading:9579902-Humans,
pubmed-meshheading:9579902-Lac Operon,
pubmed-meshheading:9579902-Transfection,
pubmed-meshheading:9579902-beta-Galactosidase
|
|
pubmed:year |
1997
|
|
pubmed:articleTitle |
Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy.
|
|
pubmed:affiliation |
Division of Neurosurgery, University of Pennsylvania School of Medicine, Philadelphia 19104-6380, USA.
|
|
pubmed:publicationType |
Journal Article
|
