Linked Life Data

9539237

Source:http://linkedlifedata.com/resource/pubmed/id/9539237

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1998-5-21
pubmed:abstractText
Deficits in speech production, sentence comprehension and abstract reasoning occurred in a subject having profound bilateral damage to the putamen and the caudate nucleus. Acoustic analyses indicated that the subject's speech was degraded due to inappropriate sequencing of articulatory gestures that involve different articulatory structures. Transitions between sounds were slow and often did not achieve target configurations. The subject had a 14% error rate comprehending distinctions in meaning conveyed by syntax in English sentences; normal controls make virtually no errors in this test. Cognitive deficits involving impaired sequencing occurred: the subject had a 70% error rate on the Odd Man Out test when making decisions within a single category. Cognitive perseveration occurred when the subject was asked to shift categories. In contrast, performance was within normal ranges in tests of lexical access and memory. The pattern of deficits provides evidence for basal ganglia involvement in the regulation of sequencing across modalities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0028-3932
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-88
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Selective speech motor, syntax and cognitive deficits associated with bilateral damage to the putamen and the head of the caudate nucleus: a case study.
pubmed:affiliation
Department of Cognitive and Linguistic Sciences, Brown University, Providence, RI, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Case Reports