Linked Life Data

9452785

Source:http://linkedlifedata.com/resource/pubmed/id/9452785

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1998-2-11
pubmed:abstractText
Hypertension has been related to the development of dementia, including Alzheimer's disease, and cognitive dysfunction in middle-aged and elderly populations. One possible explanation is that hypertension is a risk factor for cerebral infarcts and ischaemic subcortical white-matter lesions. Hypertension may also give rise to a blood-brain barrier dysfunction, which has been suggested to be involved in the aetiology and pathogenesis of Alzheimer's disease. Other possible explanations for the association are shared risk factors, such as psychological stress, and the formation of free oxygen radicals. Low blood pressure has also been hypothesized to give rise to brain damage and dementia. However, the brain is involved in blood pressure regulation and dementia disorders may therefore influence the blood pressure. The findings of an association between hypertension and dementia may have implications for prevention and treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0753-3322
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
367-75
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
The relationship between blood pressure and dementia: a review.
pubmed:affiliation
Department of Psychiatry, Sahlgrenska Hospital, Göteborg University, Sweden.
pubmed:publicationType
Journal Article, Review