Linked Life Data

9408187

Source:http://linkedlifedata.com/resource/pubmed/id/9408187

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-1-30
pubmed:abstractText
The effects of female gonadal hormones on 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)-induced flat body posture, hypothermia, and eating behavior were examined. Ovariectomized rats were injected with estradiol benzoate, estradiol benzoate, and progesterone, progesterone or vehicle on each of 2 consecutive weeks. On each week, the behavioral effects of the 5-HT1A receptor agonist, 8-OH-DPAT, or the combination of both 8-OH-DPAT and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI), a 5-HT2 receptor agonist, were examined. 8-OH-DPAT produced flat body posture, hypothermia, and eating behavior on each week of the experiment. Female gonadal hormones modulated eating behavior (e.g., rats treated with estradiol benzoate showed less eating after 8-OH-DPAT), but had no effect on either flat body posture or hypothermia. The 5-HT2 receptor agonist, DOI, attenuated 8-OH-DPAT's effect on flat body posture and on hypothermia, but not on eating behavior. 8-OH-DPAT's effect on all behaviors declined during the second week of the experiment.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
859-66
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Modulation of the behavioral effects of 8-OH-DPAT by estrogen and DOI.
pubmed:affiliation
Department of Biology, Texas Woman's University, Denton, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't