Statements in which the resource exists.
SubjectPredicateObjectContext
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pubmed-article:9375187pubmed:abstractTextEighty-five subjects at various stages of human immunodeficiency virus (HIV-1) infection and 39 seronegative controls underwent neurological and neuropsychological evaluation to assess the relationship between cognitive test results and subjective complaints (cognitive, affective, motor, and other). The effect of psychiatric disorders on the association between cognitive performance and complaints of the patients was also examined. Patients with symptomatic infection had higher frequency of complaints than subjects at asymptomatic stage. Detailed neuropsychological examination confirmed a strong association between poor verbal memory and cognitive complaints. Poor performance on cognitive speed and flexibility was associated with motor complaints and motor abnormalities. These associations were not explained by psychiatric disorders or elevated depression questionnaire scores. Our observations indicate that, especially in symptomatic HIV-1 infection cognitive changes reported by patients often reflect "objective" cognitive decline, and may be the earliest signs of HIV-1 associated cognitive disorder. No direct relationship was observed between "subjective" complaints and neuropsychological performance of asymptomatic subjects. Understanding the significance of reported cognitive changes have important therapeutic implications.lld:pubmed
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pubmed-article:9375187pubmed:pagination219-25lld:pubmed
pubmed-article:9375187pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:9375187pubmed:year1996lld:pubmed
pubmed-article:9375187pubmed:articleTitleSubjective complaints of cognitive symptoms are related to psychometric findings of memory deficits in patients with HIV-1 infection.lld:pubmed
pubmed-article:9375187pubmed:affiliationDepartment of Neurology, University of Helsinki, Finland.lld:pubmed
pubmed-article:9375187pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9375187pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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