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| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C1519424 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0032005 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0074830 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0242842 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0079603 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0449560 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0392762 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9322965 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9322965 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:9322965 | pubmed:dateCreated | 1997-10-23 | lld:pubmed |
| pubmed-article:9322965 | pubmed:abstractText | Using quantitative double-label fluorescence immunocytochemistry and confocal microscopy, we have analysed the pattern of expression of SSTR1-5 in normal rat pituitary somatotrophes. Antipeptide rabbit polyclonal antibodies were produced against the extracellular domains of SSTR1-5. SSTR antigens were colocalized in GH positive cells using rhodamine conjugated secondary antibody for SSTRs and FITC-conjugated secondary antibody for GH. SSTR5 was the predominant subtype which was expressed in 86 +/- 9.7% of GH cells followed by SSTR2 in 42 +/- 6.4% of GH positive cells. SSTR4 and SSTR3 were modestly expressed in 23 +/- 4.7% and 18 +/- 3.2% of somatotrophes respectively whereas SSTR1 was the least expressed subtype occurring in only 5 +/- 1.2% of somatotrophes. These results demonstrate variable expression of the 5 SSTRs in somatotrophes. The preponderance of the SST-28 preferring SSTR5 subtype correlates with the reported higher potency of SST-28 than SST-14 for inhibiting GH secretion. | lld:pubmed |
| pubmed-article:9322965 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9322965 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9322965 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9322965 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:9322965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9322965 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9322965 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9322965 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9322965 | pubmed:issn | 0013-7227 | lld:pubmed |
| pubmed-article:9322965 | pubmed:author | pubmed-author:PatelY CYC | lld:pubmed |
| pubmed-article:9322965 | pubmed:author | pubmed-author:EscherEE | lld:pubmed |
| pubmed-article:9322965 | pubmed:author | pubmed-author:SrikantC BCB | lld:pubmed |
| pubmed-article:9322965 | pubmed:author | pubmed-author:KumarUU | lld:pubmed |
| pubmed-article:9322965 | pubmed:author | pubmed-author:LainéMM | lld:pubmed |
| pubmed-article:9322965 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9322965 | pubmed:volume | 138 | lld:pubmed |
| pubmed-article:9322965 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9322965 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9322965 | pubmed:pagination | 4473-6 | lld:pubmed |
| pubmed-article:9322965 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:9322965 | pubmed:meshHeading | pubmed-meshheading:9322965-... | lld:pubmed |
| pubmed-article:9322965 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9322965 | pubmed:articleTitle | Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy. | lld:pubmed |
| pubmed-article:9322965 | pubmed:affiliation | Department of Medicine, McGill University, Royal Victoria Hospital and Montreal Neurological Institute, Quebec, Canada. | lld:pubmed |
| pubmed-article:9322965 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9322965 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9322965 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:9322965 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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