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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1976-9-1
|
| pubmed:abstractText |
Cefuroxime is a new broad spectrum cephalosporin antibiotic for administration by injection. It is stable to most beta-lactamases. It is active against gram-positive organisms, including penicillinase-producing staphylococci, and has wide activity against gram-negative bacilli including Enterobacter and many strains of indole-positive Proteus spp. The substance is also highly active against Haemophilus influenzae and Neisseria gonorrhoeae. Studies on human volunteers showed that it produced high, long-lasting blood levels with virtually complete recovery of unchanged antibiotic in the urine. No evidence of toxicity due to cefuroxime was found. Slight, short-lived pain followed intramuscular injection, and the compound was well tolerated intravenously.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0021-8820
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
29
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
29-37
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:931792-Bacteria,
pubmed-meshheading:931792-Blood Proteins,
pubmed-meshheading:931792-Cephalosporinase,
pubmed-meshheading:931792-Cephalosporins,
pubmed-meshheading:931792-Drug Incompatibility,
pubmed-meshheading:931792-Furans,
pubmed-meshheading:931792-Humans,
pubmed-meshheading:931792-Kinetics,
pubmed-meshheading:931792-Protein Binding
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
Cefuroxime - a new cephalosporin antibiotic.
|
| pubmed:publicationType |
Journal Article
|