Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1997-10-14
|
| pubmed:abstractText |
The coronary flow reserve is abnormal in syndrome X, but the response to the cold pressor test, which in normals produces flow-mediated endothelium-dependent epicardial coronary dilation, has not been studied. In this study, in 12 patients with typical syndrome X and angiographically normal coronary arteries, the response to the cold pressor test was abnormal with a mean fall in diameter (10 +/- 8%) in 6 patients, no change in 1, and a minimal increase (4 +/- 2%) in 5 patients (normal increase 12 +/- 1%). The coronary blood flow fell slightly during the cold pressor test, and the coronary vascular resistance increased significantly (from 2.4 +/- 1.1 to 3.2 +/- 1.7 mm Hg/cm.s-1.mm2; p = 0.05), both abnormal responses. This study confirms that in syndrome X patients there is coronary endothelial dysfunction which is apparent in response to physiological stimuli induced by the cold pressor test.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0008-6312
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
88
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
414-7
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:9286502-Adult,
pubmed-meshheading:9286502-Aged,
pubmed-meshheading:9286502-Blood Flow Velocity,
pubmed-meshheading:9286502-Blood Pressure,
pubmed-meshheading:9286502-Cold Temperature,
pubmed-meshheading:9286502-Coronary Vessels,
pubmed-meshheading:9286502-Endothelium, Vascular,
pubmed-meshheading:9286502-Female,
pubmed-meshheading:9286502-Heart Rate,
pubmed-meshheading:9286502-Humans,
pubmed-meshheading:9286502-Male,
pubmed-meshheading:9286502-Microvascular Angina,
pubmed-meshheading:9286502-Middle Aged,
pubmed-meshheading:9286502-Nitroglycerin,
pubmed-meshheading:9286502-Rheology,
pubmed-meshheading:9286502-Vascular Resistance,
pubmed-meshheading:9286502-Vasoconstriction,
pubmed-meshheading:9286502-Vasodilation
|
| pubmed:articleTitle |
Endothelium-dependent dilation of the coronary arteries in syndrome X: effects of the cold pressor test.
|
| pubmed:affiliation |
Department of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital.
|
| pubmed:publicationType |
Journal Article
|