Linked Life Data

9263772

Source:http://linkedlifedata.com/resource/pubmed/id/9263772

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-10-23
pubmed:abstractText
The distribution of glutathione S-transferase T1 (GSTT1) phenotypes was studied in a total sample of 673 Estonians whose four grandparents were born in Estonia, by an ELISA test able to differentiate between GSTT1 positive and GSTT1 negative phenotypes. 18% of the total sample did not present GSTT1-1 protein in whole blood. GSTT1-1 concentration was assayed in 519 out of the 552 GSTT1 positive subjects (i.e. 82% of the total sample) 49% percent of this subsample made up by 519 subjects was found to have GSTT1-1 in intermediate concentration and 33% in high concentration. The gene frequency of the GSTT1 deleted allele was estimated to be 0.423 as the square root of the frequency of the GSTT1 negative subjects (square root of 0.18 = 0.423) and that of the GSTT1 positive allele as (1-0.423) = 0.577. Statistically significant regional differences were found within the population with the lowest frequency of GSTT1 negative in western Estonia (9.5%) and the highest in the southeastern part of the country (24.5%).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0394-249X
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Distribution of glutathione S-transferase T1 phenotypes in the Estonian population.
pubmed:affiliation
Department of Human Biology and Genetics, Tartu University, Estonia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't