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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1997-9-11
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pubmed:abstractText |
The efficacy and safety of two different regimens for parenteral treatment of presumed severe febrile urinary tract infection were compared in a randomized study. One hundred fifty-eight patients were treated with either cefotaxime 2 g i.v. twice daily for at least two days followed by norfloxacin 400 mg twice daily orally or one bolus dose of gentamicin 3 mg/kg i.v. and norfloxacin from the start. Three patients randomized to cefotaxime died. Of the 101 patients with verified urinary tract infection, clinical response to assigned therapy was seen in 79% and 74%, respectively. There was no difference in fever duration between the two regimens. The results indicate that one bolus dose of gentamicin with early oral therapy is a safe and effective alternative to common parenteral regimens for empirical treatment of febrile urinary tract infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
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pubmed:issn |
0934-9723
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
455-8
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:9248749-Adult,
pubmed-meshheading:9248749-Aged,
pubmed-meshheading:9248749-Aged, 80 and over,
pubmed-meshheading:9248749-Cefotaxime,
pubmed-meshheading:9248749-Drug Therapy, Combination,
pubmed-meshheading:9248749-Female,
pubmed-meshheading:9248749-Fever,
pubmed-meshheading:9248749-Gentamicins,
pubmed-meshheading:9248749-Humans,
pubmed-meshheading:9248749-Male,
pubmed-meshheading:9248749-Middle Aged,
pubmed-meshheading:9248749-Norfloxacin,
pubmed-meshheading:9248749-Prospective Studies,
pubmed-meshheading:9248749-Urinary Tract Infections
|
pubmed:year |
1997
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pubmed:articleTitle |
One bolus dose of gentamicin and early oral therapy versus cefotaxime and subsequent oral therapy in the treatment of febrile urinary tract infection.
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pubmed:affiliation |
Department of Infectious Diseases, Orebro Medical Center Hospital, Sweden.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|