|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5-6
|
|
pubmed:dateCreated |
1997-8-28
|
|
pubmed:abstractText |
Pulvinatal (1) was isolated from fermentations of Nidularia pulvinata as an inducer of differentiation of HL-60 promyelocytic leukemia cells. Its structure was elucidated by spectroscopic methods. In addition, N. pulvinata was found to produce 2,4,5-trihydroxy-6-methyl-benzenecarbaldehyde (2) and orsellinic acid (3). Pulvinatal exhibits weak antifungal and only marginal cytotoxic activities.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0939-5075
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
52
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
313-8
|
|
pubmed:dateRevised |
2009-11-4
|
|
pubmed:meshHeading |
pubmed-meshheading:9232889-Antifungal Agents,
pubmed-meshheading:9232889-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:9232889-Basidiomycota,
pubmed-meshheading:9232889-Cell Differentiation,
pubmed-meshheading:9232889-Fermentation,
pubmed-meshheading:9232889-Fungi,
pubmed-meshheading:9232889-HL-60 Cells,
pubmed-meshheading:9232889-Humans,
pubmed-meshheading:9232889-Microbial Sensitivity Tests,
pubmed-meshheading:9232889-Molecular Structure,
pubmed-meshheading:9232889-Pyrans,
pubmed-meshheading:9232889-Tumor Cells, Cultured
|
|
pubmed:articleTitle |
Pulvinatal, a novel bioactive metabolite from the basidiomycete Nidularia pulvinata (Schw.) Fr.
|
|
pubmed:affiliation |
Lehrbereich Biotechnologie, Universität Kaiserslautern, Germany.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
