Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-10-1
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pubmed:abstractText |
We report a 34-year-old woman with juvenile parkinsonism who had been treated with five tablets daily of l-dopa/benserazide (100 mg/25 mg). She became pregnant in May 1995 and continued the same treatment. She delivered a healthy boy (3,798 g, 52 cm) with Apgar scores of 9 at 38 weeks gestation by normal delivery. In animal study, there is a report of teratogenicity (bone abnormality) of l-dopa/benserazide in rabbits at doses of 30 mg/kg and 120 mg/kg. However, there have been several reports of uneventful delivery of normal children in patients with juvenile parkinsonism who had been treated with l-dopa/decarboxylase inhibitor (DCI) during pregnancy. There seems to be no firm reason to avoid pregnancy during the treatment of l-dopa/DCI or to withhold l-dopa/DCI during pregnancy.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0009-918X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
264-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9217430-Adult,
pubmed-meshheading:9217430-Animals,
pubmed-meshheading:9217430-Antiparkinson Agents,
pubmed-meshheading:9217430-Benserazide,
pubmed-meshheading:9217430-Carbonic Anhydrase Inhibitors,
pubmed-meshheading:9217430-Drug Therapy, Combination,
pubmed-meshheading:9217430-Female,
pubmed-meshheading:9217430-Humans,
pubmed-meshheading:9217430-Infant, Newborn,
pubmed-meshheading:9217430-Levodopa,
pubmed-meshheading:9217430-Male,
pubmed-meshheading:9217430-Parkinson Disease,
pubmed-meshheading:9217430-Pregnancy,
pubmed-meshheading:9217430-Pregnancy Complications,
pubmed-meshheading:9217430-Rabbits
|
pubmed:year |
1997
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pubmed:articleTitle |
[L-dopa/benserazide during pregnancy in a patient with juvenile parkinsonism].
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pubmed:affiliation |
Department of Neurology, School of Medicine, Chiba University.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|