Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1997-9-5
pubmed:abstractText
The appearance of autoantibodies to nuclear autoantigens is the hallmark of systemic autoimmune diseases. The mechanism of the autoantibody production has remained elusive, though it is generally accepted that autoantigen-specific T cells drive the production. These autoantigen-specific T cells as well as autoreactive B cells can be found in peripheral blood from healthy people, suggesting that these autoreactive cells are regulated peripherally. In this review dealing with autoantibody production mechanism, the brief introduction of our approach employing mouse genetics is also included.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0047-1852
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1468-74
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[The mechanism of autoantibody production in systemic autoimmune diseases].
pubmed:affiliation
Department of Clinical Immunology, Kyushu University.
pubmed:publicationType
Journal Article, English Abstract, Review