Linked Life Data

9179273

Source:http://linkedlifedata.com/resource/pubmed/id/9179273

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1997-7-10
pubmed:abstractText
Leukemia is a heterogeneous collection of diseases with different molecular origins. The molecular features may provide physicians with markers that can be used to monitor disease. In acute lymphoblastic leukemia (ALL), molecular monitoring methods can be very useful in developing and improving treatment. Some argue that one of the main problems in adult ALL is that it is homogeneous but, in fact, it is a very diverse condition. However, it can't be seen in the surface markers or in the nucleus of these diseases, so there is a need to develop ways to identify these cases. Good and potentially curable subsets of ALL patients are beginning to be identified by combining traditional phenotypic and immunologic markers with molecular and genetic approaches. As treatments improve, definition of therapeutic and prognostic subsets and their significance to clinical outcome is imperative. While progress has been made in the use of molecular techniques to detect residual disease, we must still acquire experience in using these markers to monitor treatment efficacy, with the eventual aim of improving outcome.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0887-6924
pubmed:author
pubmed:issnType
Print
pubmed:volume
11 Suppl 4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S8-10
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Molecular subsets and prognostic factors in acute lymphoblastic leukemia.
pubmed:affiliation
Section of Hematology/Oncology, University of Illinois, Chicago 60607, USA.
pubmed:publicationType
Journal Article, Review