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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-7-28
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pubmed:abstractText |
The radiotracer [123I]beta-CIT is a sensitive marker of dopamine uptake sites that can be used to visualize dopaminergic nerve endings in vivo in the human brain. We report on [123I]beta-CIT single-photon emission computed tomography (SPECT) findings in a patient with DOPA-responsive dystonia (DRD). [123I]beta-CIT SPECT showed a striatal radiotracer uptake in the upper range of normal, indicating intact dopamine transporters and structural integrity of nigrostriatal neurons. This differentiates DRD from clinically similar cases with juvenile-onset parkinsonism with dystonia that have a considerable poorer prognosis. [123I]-beta-CIT SPECT may provide a method equally as useful as fluorodopa positron emission tomography in DRD.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0885-3185
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
448-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9159746-Adult,
pubmed-meshheading:9159746-Aged,
pubmed-meshheading:9159746-Binding Sites,
pubmed-meshheading:9159746-Cerebellum,
pubmed-meshheading:9159746-Corpus Striatum,
pubmed-meshheading:9159746-Diagnosis, Differential,
pubmed-meshheading:9159746-Dopamine,
pubmed-meshheading:9159746-Dystonia,
pubmed-meshheading:9159746-Female,
pubmed-meshheading:9159746-Humans,
pubmed-meshheading:9159746-Levodopa,
pubmed-meshheading:9159746-Middle Aged,
pubmed-meshheading:9159746-Radioactive Tracers,
pubmed-meshheading:9159746-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
1997
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pubmed:articleTitle |
[123I]beta-CIT single-photon emission tomography in DOPA-responsive dystonia.
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pubmed:affiliation |
Department of Neurology, Universities of Würzburg, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Case Reports
|