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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1977-12-29
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pubmed:abstractText |
Metabolism of N-nitrosodi-n-propylamine by an isolated rat liver microsomal fraction yielded 17% isopropanol and 83% n-propanol (expressed as a percentage of total propanol formed). Base-catalyzed decomposition of N-n-propyl-N-nitrosourea yielded 39% isopropanol and 61% n-propanol. The values provide evidence for involvement of carbocations in both of these reactions.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0009-2797
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
349-54
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:912817-Alcohols,
pubmed-meshheading:912817-Alkylation,
pubmed-meshheading:912817-Animals,
pubmed-meshheading:912817-Isomerism,
pubmed-meshheading:912817-Male,
pubmed-meshheading:912817-Microsomes, Liver,
pubmed-meshheading:912817-Nitroso Compounds,
pubmed-meshheading:912817-Nitrosourea Compounds,
pubmed-meshheading:912817-Oxidation-Reduction,
pubmed-meshheading:912817-Propylamines,
pubmed-meshheading:912817-Rats
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pubmed:year |
1977
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pubmed:articleTitle |
Mechanism of alkylation by N-nitroso compounds: detection of rearranged alcohol in the microsomal metabolism of N-nitrosodi-n-propylamine and base-catalyzed decomposition of N-n-propyl-N-nitrosourea.
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pubmed:publicationType |
Journal Article,
In Vitro
|