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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1997-4-24
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pubmed:abstractText |
A 36-year-old man had an oval, black, extradural tumor partly removed from the left C4 spinal root, with total removal 4 months later. In both specimens, most tumor cells were spindle-shaped. A few cells were large, epithelioid-like, with a prominent nucleolus. Mitoses were rarely seen. Many tumor cells contained coarse or fine granules of a brown pigment. Such cells were immunopositive for S-100 protein and HMB-45. Additionally, psammoma bodies were numerous in certain areas, indicating a diagnosis of psammomatous melanotic schwannoma (PMS). Periumbilical spotty pigmentation was found in the patient and in six of his siblings and their mother. The search for cardiac myxoma and endocrine overactivity was negative in the patient. Features of Carney's complex must be sought in a patient with PMS and in their primary relatives. So far, more than 150 patients and seven families with Carney's complex have been reported.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0344-0338
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
192
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1142-6; discussion 1147
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9122034-Adult,
pubmed-meshheading:9122034-Humans,
pubmed-meshheading:9122034-Immunohistochemistry,
pubmed-meshheading:9122034-Male,
pubmed-meshheading:9122034-Microscopy, Electron,
pubmed-meshheading:9122034-Neurilemmoma,
pubmed-meshheading:9122034-Peripheral Nervous System Neoplasms,
pubmed-meshheading:9122034-Pigmentation Disorders,
pubmed-meshheading:9122034-Spinal Nerve Roots,
pubmed-meshheading:9122034-Syndrome
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pubmed:year |
1996
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pubmed:articleTitle |
Psammomatous melanotic schwannoma of a spinal nerve root. Relationship with the Carney complex.
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pubmed:affiliation |
Neuropathology Department, Bordeaux II University, France.
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pubmed:publicationType |
Journal Article,
Case Reports
|