Linked Life Data

9091763

Source:http://linkedlifedata.com/resource/pubmed/id/9091763

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1997-4-8
pubmed:abstractText
The biological indicators that have been proposed for monitoring occupational exposure are: concentration of the solvent or metabolized compounds in alveolar or expired air samples, in venous or arterial capillary blood samples and in urine samples. Recently, many researches have reported significant relationships between the time-weighted average exposure and the urinary concentrations for various solvents. The aim of our study was to compare two methods in which urinary concentrations of pseudocumene were determined by gas chromatography using headspace technique. The standard method was based on determining concentration of organic solvents in 100 mm3 or 1 cm3 samples of urine. The incubation conditions were as follows: equilibration temperature and time: 70 degrees C, 30 min., respectively. 1 cm3 of gas phase was sampled with a gas-tight syringe and injected into a gas chromatograph. The new method using Headspace Sampler was based on determining concentrations of solvents in 10 cm3 samples of urine. The operating conditions were: equilibration time 30 min.; equlibration temperature 80 degrees C; pressurization time 0.1 min.; loop fill time 0.1 min.; loop equilibration 0.1 min.; loop equilibration time 0.05 min.; inject time 1 min.; loop temperature 150 degrees C, transfer line temperature 150 degrees C. HP 7694 Headspace Sampler minimizes sample degradation with a chemically inert pathway extending from the sample loop to the column head. The analytical parameters of both methods (linearity, precision, reproducibility, stability and sensitivity) are fully compatible with the principles of biological monitoring. Application of the headspace autosampler eliminated interference from the biological matrix and made it possible to achieve very low detection limit.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0465-5893
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
605-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
[Comparison of standard methods for determination of pseudocumene in urine using gas chromatography with the headspace technique and a new method using a headspace automatic sampler].
pubmed:affiliation
Zak?adu Monitoringu Biologicznego, Instytutu Medycyny Pracy, Lodzi.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract