Linked Life Data

9074520

Source:http://linkedlifedata.com/resource/pubmed/id/9074520

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-4-9
pubmed:abstractText
Overexpression of the multidrug resistance (MDR1) P-glycoprotein (Pgp) has been documented in nearly all forms of human cancers and increased levels of Pgp in some tumors correlate with poor response to treatment. Technetium-99m-sestamibi has recently been validated as a Pgp transport substrate. Pgp is also normally expressed along the biliary canalicular surface of hepatocytes and the luminal side of proximal tubule cells in the kidney, while not expressed in heart.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0161-5505
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
369-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9074520-Adenocarcinoma, pubmed-meshheading:9074520-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:9074520-Breast Neoplasms, pubmed-meshheading:9074520-Carcinoma, Ductal, Breast, pubmed-meshheading:9074520-Cyclosporins, pubmed-meshheading:9074520-Cystadenocarcinoma, pubmed-meshheading:9074520-Drug Resistance, Multiple, pubmed-meshheading:9074520-Female, pubmed-meshheading:9074520-Humans, pubmed-meshheading:9074520-Kidney, pubmed-meshheading:9074520-Liver, pubmed-meshheading:9074520-Lung Neoplasms, pubmed-meshheading:9074520-Middle Aged, pubmed-meshheading:9074520-Neoplasm Recurrence, Local, pubmed-meshheading:9074520-Ovarian Neoplasms, pubmed-meshheading:9074520-P-Glycoprotein, pubmed-meshheading:9074520-Paclitaxel, pubmed-meshheading:9074520-Technetium Tc 99m Sestamibi
pubmed:year
1997
pubmed:articleTitle
Modulation of the multidrug resistance P-glycoprotein: detection with technetium-99m-sestamibi in vivo.
pubmed:affiliation
Mallinckrodt Institute of Radiology, Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Missouri, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, Non-P.H.S., Case Reports, Research Support, Non-U.S. Gov't, Clinical Trial, Phase I