|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1996-12-12
|
|
pubmed:abstractText |
Nearly all human sera contain an immunoglobulin G antibody (antigalactose) that binds the trisaccharide Gal alpha 1-3Gal beta 1-4GlcNAc expressed on cells from most mammals but not humans. Because the Clostridium difficile toxin A receptor in rodents contains this trisaccharide, the aim of this study was to examine whether antigalactose could mimic the enterotoxic effects of toxin A and bind to receptors containing this trisaccharide.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Toxins,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Enterotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Griffonia simplicifolia lectins,
http://linkedlifedata.com/resource/pubmed/chemical/Lectins,
http://linkedlifedata.com/resource/pubmed/chemical/Metalloendopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Lectins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/auR protein, Staphylococcus aureus,
http://linkedlifedata.com/resource/pubmed/chemical/galactose receptor,
http://linkedlifedata.com/resource/pubmed/chemical/tcdA protein, Clostridium difficile
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0016-5085
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
110
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1704-12
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:8964394-Animals,
pubmed-meshheading:8964394-Antibodies,
pubmed-meshheading:8964394-Bacterial Toxins,
pubmed-meshheading:8964394-Colon,
pubmed-meshheading:8964394-Dinoprostone,
pubmed-meshheading:8964394-Enterotoxins,
pubmed-meshheading:8964394-Humans,
pubmed-meshheading:8964394-Lectins,
pubmed-meshheading:8964394-Male,
pubmed-meshheading:8964394-Mast Cells,
pubmed-meshheading:8964394-Metalloendopeptidases,
pubmed-meshheading:8964394-Microvilli,
pubmed-meshheading:8964394-Plant Lectins,
pubmed-meshheading:8964394-Rats,
pubmed-meshheading:8964394-Rats, Wistar,
pubmed-meshheading:8964394-Receptors, Cell Surface
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon.
|
|
pubmed:affiliation |
Section of Gastroenterology, Evans Memorial Department of Clinical Research, Boston University School of Medicine, Massachusetts, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
