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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1997-3-5
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pubmed:abstractText |
Dextrorphan is a noncompetitive blocker of N-methyl-D-aspartate (NMDA) receptors. Since NMDA blockers are known to reduce the locomotor stimulatory and toxic effects of cocaine, it was speculated that dextrorphan would attenuate cocaine-induced behavioral excitatory motor activity associated with and without mechanical perturbation of the brainstem.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
1053-881X
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
224-30
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:8894724-Animals,
pubmed-meshheading:8894724-Arousal,
pubmed-meshheading:8894724-Brain Stem,
pubmed-meshheading:8894724-Cocaine,
pubmed-meshheading:8894724-Dextrorphan,
pubmed-meshheading:8894724-Electrodes, Implanted,
pubmed-meshheading:8894724-Electroencephalography,
pubmed-meshheading:8894724-Escape Reaction,
pubmed-meshheading:8894724-Excitatory Amino Acid Antagonists,
pubmed-meshheading:8894724-Infusion Pumps,
pubmed-meshheading:8894724-Injections, Intraperitoneal,
pubmed-meshheading:8894724-Injections, Subcutaneous,
pubmed-meshheading:8894724-Motor Activity,
pubmed-meshheading:8894724-Narcotics,
pubmed-meshheading:8894724-Rats,
pubmed-meshheading:8894724-Rats, Inbred SHR,
pubmed-meshheading:8894724-Receptors, N-Methyl-D-Aspartate
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pubmed:articleTitle |
Dextrorphan effects on cocaine and brainstem perturbation.
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pubmed:affiliation |
Dept. of Neurosurgery, U. of Mississippi Med Center, Jackson 39126, USA.
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pubmed:publicationType |
Journal Article
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