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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1996-11-8
|
| pubmed:abstractText |
It has been previously demonstrated that the sea star axial organ is a primitive immune organ. Phagocytic, lymphoid-like cells have been characterized with properties similar to those of vertebrates. There is also evidence for an invertebrate cytokine network because IL-1 and TNF-like activities are clearly demonstrable. In addition, the authors have previously described preliminary evidence for IL-2-like activity in the sea star. In the present report, the authors obtained evidence for the presence of IL-1- and IL-2-like molecules on axial organ cells. More interestingly, the results suggested that sea star cells express structures similar to human receptors for IL-1, IL-2, IL-6 and IFN-gamma.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0300-9475
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
44
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
375-80
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8845031-Animals,
pubmed-meshheading:8845031-Antibodies, Monoclonal,
pubmed-meshheading:8845031-Cytokines,
pubmed-meshheading:8845031-Hemocyanin,
pubmed-meshheading:8845031-Lymphoid Tissue,
pubmed-meshheading:8845031-Phenotype,
pubmed-meshheading:8845031-Receptors, Cytokine,
pubmed-meshheading:8845031-Starfish,
pubmed-meshheading:8845031-Stimulation, Chemical
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Primitive cytokines and cytokine receptors in invertebrates: the sea star Asterias rubens as a model of study.
|
| pubmed:affiliation |
Department of Hematology, Centre Hospitalier Régional d'Orléans, France.
|
| pubmed:publicationType |
Journal Article
|