Linked Life Data

8836489

Source:http://linkedlifedata.com/resource/pubmed/id/8836489

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-12-17
pubmed:abstractText
Gonadotropin-releasing hormone (GnRH) plays a major role in the endocrine control of reproduction. GnRH, released from the hypothalamus, acts upon the pituitary to stimulate LH and FSH secretion. In addition, GnRH also functions as a local regulator in a number of tissues and cell lines. GnRH interacts with a membrane receptor which belongs to the G-protein-coupled receptor family. The GnRH-R is encoded by a single-copy gene consisting of three exons and two introns. Consistent with the sites of its action, GnRH-R mRNA has been found in the brain, pituitary, gonads, placenta, as well as a number of carcinoma tissues and cells. GnRH-R mRNA level in the pituitary and gonads is controlled by a number of physiological regulators, such as GnRH, gonadotropin, estradiol and progesterone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1016-0922
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Gonadotropin-releasing hormone receptor: gene structure, expression and regulation.
pubmed:affiliation
Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, Canada.
pubmed:publicationType
Journal Article, Review