Linked Life Data

8817928

Source:http://linkedlifedata.com/resource/pubmed/id/8817928

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-10-30
pubmed:databankReference
pubmed:abstractText
Transferrin is a monomeric iron-binding glycoprotein. To investigate the structure of the transferrin gene in teleosts, we prepared a genomic DNA library from the medaka (Oryzias latipes). The medaka transferrin gene was isolated, and its nucleotide sequence was determined. The full length of this gene is approximately 8.5 kb, and it is organized into 17 exons separated by 16 introns. The exons are similar in size to those in the genes for human transferrin, chicken ovotransferrin, and mouse and bovine lactoferrin. However, the introns are smaller than those previously reported in the transferrin family of genes. The 5'-flanking region of the medaka transferrin gene contains an estrogen-responsive element, glucocorticoid-responsive elements, an iron-responsive element, metal-responsive elements, and Sp1 binding sites. The transcription start point is located 35 bp upstream of the start codon.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1053-6426
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Structure of medaka transferrin gene and its 5'-flanking region.
pubmed:affiliation
Laboratory of Genetics and Biochemistry, Tokyo, University of Fisheries, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't