Linked Life Data

8788095

Source:http://linkedlifedata.com/resource/pubmed/id/8788095

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1996-10-25
pubmed:abstractText
Taste interactions between salts (NaCl, LiCl, KCl, L-arginine:L-aspartic acid, Na-acetate and Na-gluconate) and bitter-tasting compounds (urea, quinine HCl, magnesium sulphate, KCl, amiloride HCl and caffeine) were investigated. In each study binary combinations of three or four concentrations of one bitter compound with four concentrations (0, 0.1, 0.3 and 0.5 M) of one salt were rated for bitterness and saltiness using the method of magnitude estimation. In most cases, perceived bitterness was suppressed by salts, although the degree of suppression varied. In general, bitterness suppression was not accompanied by an equivalent reciprocal suppression of saltiness. Only MgSO4 and amiloride had suppressing effects on the saltiness of NaCl at the intermediate concentrations and no bitter compound affected the saltiness at the high concentrations of NaCl. Since salt suppressed the bitterness of urea effectively, a detailed analysis of suppression of the bitterness of urea by different salts was conducted. Those studies indicated that the key component in this effect was the sodium or lithium ion for two reasons: first, all three sodium salts and the lithium salt had a suppressive effect on bitterness, whereas KCl did not; secondly, the effect of a salt on suppression of the bitterness of urea was independent of its perceived saltiness; that is, NaCl, Na-acetate (which is perceived as less salty than NaCl), and Na-gluconate (which is perceived as less salty than Na-acetate) reduced bitterness comparably. These results suggest that there is a major peripheral component to the suppression of the bitterness of urea, and perhaps other bitter tasting compounds, by sodium.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0379-864X
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
609-23
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Suppression of bitterness by sodium: variation among bitter taste stimuli.
pubmed:affiliation
Monell Chemical Senses Center, Philadelphia, PA 19104-3308, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.