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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1996-9-17
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pubmed:abstractText |
Two previous phase II trials of docetaxels as first line chemotherapy of advanced breast cancer have been conducted by the Clinical Screening Group of the EORTC. In these 2 studies, docetaxel 100 mg/m2 and 75 mg/m2 were administered without routine premedication and produced overall response rates of 68% and 52% respectively. Fluid retention was the most problematic adverse event in these 2 studies in which premedication was not routinely administered. This study investigated the efficacy and safety profile of docetaxel with a 1-day prophylactic premedication.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0923-7534
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8777173-Adult,
pubmed-meshheading:8777173-Aged,
pubmed-meshheading:8777173-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:8777173-Breast Neoplasms,
pubmed-meshheading:8777173-Confidence Intervals,
pubmed-meshheading:8777173-Dose-Response Relationship, Drug,
pubmed-meshheading:8777173-Female,
pubmed-meshheading:8777173-Humans,
pubmed-meshheading:8777173-Infusions, Intravenous,
pubmed-meshheading:8777173-Middle Aged,
pubmed-meshheading:8777173-Paclitaxel,
pubmed-meshheading:8777173-Survival Rate,
pubmed-meshheading:8777173-Taxoids,
pubmed-meshheading:8777173-Treatment Outcome
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pubmed:year |
1996
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pubmed:articleTitle |
A multicentre phase II study of the efficacy and safety of docetaxel as first-line treatment of advanced breast cancer: report of the Clinical Screening Group of the EORTC.
|
pubmed:affiliation |
Centre Régionale de Lutte Contre le Cancer, Nantes Atlantique-ICERC, Saint Herblain, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
|