Linked Life Data

8747422

Source:http://linkedlifedata.com/resource/pubmed/id/8747422

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1996-10-9
pubmed:abstractText
A 13-year-old male with adrenoleukodystrophy (ALD) developed a sleep-wake disorder after complete vision loss. He had a 25-h sleep-wake cycle. After methyl B12 therapy, circadian rhythms in his plasma melatonin and beta-endorphin levels approximated those of healthy volunteers, and his peak cortisol time shifted backward. Daily deep body temperature (DBT) amplitude was smaller than in healthy males before and after the treatment, and his acrophase did not change. However, his sleep-wake rhythm became normal. Methyl B12 is considered useful for treating circadian rhythm disturbances in patients having central nervous system disorders and blindness.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0387-7604
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
428-31
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Circadian rhythm abnormalities in adrenoleukodystrophy and methyl B12 treatment.
pubmed:affiliation
Department of Child Development, Kumamoto University School of Medicine, Japan.
pubmed:publicationType
Journal Article, Case Reports