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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1996-7-22
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pubmed:abstractText |
There are no controlled clinical trials evaluating drug therapy in patients with ventricular arrhythmias and chronic chagasic cardiomyopathy. Empirical treatment with disopyramide (400-1, 1,000mg/d), phenytoin (4-6mg/d), mexiletine 600-1,200mg/d), propafenone (900mg/d), amiodarone (loading: 1,000mg/d, 10-14 days; maintenance 200-600mg/d), and sotalol (320mg/d) had efficacy and tolerance ranging from 18% to 90% with heterogeneous criteria for efficacy definition. Further studies with homogenous criteria are required to determine which is most appropriate drug therapy for patients with chronic chagasic cardiomyopathy and ventricular arrhythmias.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1516-3180
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
113
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
858-61
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8650487-Anti-Arrhythmia Agents,
pubmed-meshheading:8650487-Arrhythmias, Cardiac,
pubmed-meshheading:8650487-Chagas Cardiomyopathy,
pubmed-meshheading:8650487-Chronic Disease,
pubmed-meshheading:8650487-Humans,
pubmed-meshheading:8650487-Prognosis,
pubmed-meshheading:8650487-Tachycardia, Ventricular
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pubmed:articleTitle |
Medical treatment of cardiac arrhythmias in Chagas' heart disease.
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pubmed:affiliation |
Escola Paulista de Medicina - São Paulo, Brazil.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Review
|