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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1977-7-29
|
| pubmed:abstractText |
Twenty-eight children aged five to nine years with chronic serous otitis media received a single dose of either ampicillin or amoxicillin by the oral route 1-2 hr before the removal of middle ear fluid by ventilation tubes inserted through the tympanic membrane. At the time middle ear fluid was obtained, a sample of blood was drawn from the patient, and levels of antibiotic in both specimens were microbiologically assayed by a disk diffusion method. Levels of amoxicillin (mean+/-standard error [SE], 1.48+/-1.6 microng/ml) in middle ear fluid were consistently and significantly higher (P less than 0.05) than levels of ampicillin (mean+/-SE, 6.2+/-5.0 microng/ml).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
135
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
999-1002
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:864293-Administration, Oral,
pubmed-meshheading:864293-Amoxicillin,
pubmed-meshheading:864293-Ampicillin,
pubmed-meshheading:864293-Child,
pubmed-meshheading:864293-Chronic Disease,
pubmed-meshheading:864293-Exudates and Transudates,
pubmed-meshheading:864293-Female,
pubmed-meshheading:864293-Humans,
pubmed-meshheading:864293-Male,
pubmed-meshheading:864293-Otitis Media
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Comparison of concentrations of amoxicillin and ampicillin in serum and middle ear fluid of children with chronic otitis media.
|
| pubmed:publicationType |
Journal Article
|