Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1996-5-17
|
| pubmed:abstractText |
The combined experience of four university medical centers with fine-needle aspiration biopsy (FNAB) of the mediastinum is reviewed. This series includes 189 cases, with 100 males and 89 females, 6 months to 86 years of age. The majority (71%) of diagnoses were neoplastic with the remainder equally distributed between nondiagnostic/unsatisfactory and nonneoplastic lesions. Malignant lymphoma and thymoma were the most frequent primary malignancies. Metastatic tumors represented the majority (60%) of neoplasms identified by FNAB. In 16% of these cases, the primary tumor was not identified. The majority (67%) of metastases were from the lung and were predominantly small cell type (52%). Sixty-six ancillary tests were performed on 51 cases (27%). Histologic correlation was available in 78 of 189 (41%) cases, with a diagnostic sensitivity and specificity of 87% to 88% for the detection of neoplasm and 82% to 83% for distinguishing benign from malignant disease. The positive predictive value for the presence of neoplasm was 97% with three cytologic false positives identified. This series is the largest to date on the utility of FNAB for lesions of the mediastinum.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0002-9173
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
105
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
168-73
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8607440-Adolescent,
pubmed-meshheading:8607440-Adult,
pubmed-meshheading:8607440-Aged,
pubmed-meshheading:8607440-Aged, 80 and over,
pubmed-meshheading:8607440-Biopsy, Needle,
pubmed-meshheading:8607440-Child,
pubmed-meshheading:8607440-Child, Preschool,
pubmed-meshheading:8607440-Cytodiagnosis,
pubmed-meshheading:8607440-Female,
pubmed-meshheading:8607440-Flow Cytometry,
pubmed-meshheading:8607440-Humans,
pubmed-meshheading:8607440-Immunohistochemistry,
pubmed-meshheading:8607440-Infant,
pubmed-meshheading:8607440-Male,
pubmed-meshheading:8607440-Mediastinal Diseases,
pubmed-meshheading:8607440-Mediastinal Neoplasms,
pubmed-meshheading:8607440-Mediastinum,
pubmed-meshheading:8607440-Microscopy, Electron,
pubmed-meshheading:8607440-Middle Aged,
pubmed-meshheading:8607440-Neoplasm Metastasis
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Fine-needle aspiration biopsy of the mediastinum. A multi-institutional analysis.
|
| pubmed:affiliation |
Department of Pathology, SUNY Health Science Center 13210, USA.
|
| pubmed:publicationType |
Journal Article,
Multicenter Study
|