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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1977-6-30
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pubmed:abstractText |
Autologous plasma, when exposed to complement-activating agents that generate leukotactic activity, induces transient neutropenia after infusion into rabbits. Trypsinized human C5 as well as the chemotactic fragment isolated from zymosan-activated human serum also induces transient neutropenia in rabbits, as do chemotactically active synthetic tripeptides. In each instance the neutropenia-inducing activity parallels the chemotactic activity. Thus, neutropenia-inducing activity and chemotactic activity seem to be related physiologic responses of neutrophils. In vivo margination and/or agglutination of leukocytes may underlie this phenomenon of neutropenia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0022-1767
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
118
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1586-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:858915-Agranulocytosis,
pubmed-meshheading:858915-Animals,
pubmed-meshheading:858915-Antibodies,
pubmed-meshheading:858915-Chemotaxis, Leukocyte,
pubmed-meshheading:858915-Complement C5,
pubmed-meshheading:858915-Infusions, Parenteral,
pubmed-meshheading:858915-Leukocytes,
pubmed-meshheading:858915-Neutropenia,
pubmed-meshheading:858915-Neutrophils,
pubmed-meshheading:858915-Rabbits,
pubmed-meshheading:858915-Snake Venoms
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pubmed:year |
1977
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pubmed:articleTitle |
Neutropenia induced by systemic infusion of chemotactic factors.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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