Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-2-20
pubmed:abstractText
The serum concentration of the cell proliferation marker TPS (Tissue Polypeptide-Specific Antigen) was compared with 7 different common tumor markers (CEA, CA 12-5, CA 19-9, CA 15-3, ferritin, AFP and beta 2-Microglobulin) in order to assess its practical value in the management of breast cancer. The new monoclonal TPS assay utilizing the specific epitope M3 is used to monitor cell multiplication in cancer patients. The values are not related to tumor burden but rather reflect the tumor proliferation rate. In our study no association was found between the TPS values and the age of the patients and histologic tumor types. Significant correlation was observed between the TPS values and the menopausal status of the patient. The regression analyses between TPS and the other markers did not reveal a correlation. Association between the TPS values and the CA 15-3 was not found. However, strong correlation between CA 15-3 and four other markers was observed. Therefore, it was concluded that TPS can provide additional information when used in combination with CA 15-3.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0392-2936
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
363-7
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
The value of TPS in breast cancer.
pubmed:affiliation
I.U. Oncology Institute, Department of Basic Oncology Istanbul, Turkey.
pubmed:publicationType
Journal Article