Linked Life Data

8505194

Source:http://linkedlifedata.com/resource/pubmed/id/8505194

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-7-2
pubmed:abstractText
Women are at a greater risk compared to men for blinding complications from trachoma. In order to evaluate risk factors in women, 205 cases of trichiasis (TT) were selected from 11 villages in rural Tanzania. Each case of trichiasis was matched to two women of the same age and from the same village, who had no clinical signs of trachoma. Factors associated with trichiasis in a conditional logistic regression included history of trichiasis in the women's mother (odds ratio [OR] = 3.6; 95% confidence interval [CI]: 2.0-6.5); sleeping in a room with a cooking fire during childbearing years (OR = 1.8; 95% CI: 1.2-2.8); a home of wood and earth during childbearing years (OR = 2.1; 95% CI: 1.3-3.3); no adult education classes (OR = 2.2; 95% CI: 1.4-3.4); and five or more deaths among her children (OR = 2.6; 95% CI: 1.3-5.1). Detailed measures of prolonged exposure to child care as a young girl and as a mother showed no significant difference between cases and controls. Results from this study characterize women at high risk for severe disease and eventual blindness in a trachoma endemic area.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Africa, http://linkedlifedata.com/resource/pubmed/keyword/Africa South Of The Sahara, http://linkedlifedata.com/resource/pubmed/keyword/Biology, http://linkedlifedata.com/resource/pubmed/keyword/Case Control Studies, http://linkedlifedata.com/resource/pubmed/keyword/Chlamydia--women, http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries, http://linkedlifedata.com/resource/pubmed/keyword/Diseases, http://linkedlifedata.com/resource/pubmed/keyword/Eastern Africa, http://linkedlifedata.com/resource/pubmed/keyword/Economic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Education, http://linkedlifedata.com/resource/pubmed/keyword/English Speaking Africa, http://linkedlifedata.com/resource/pubmed/keyword/Geographic Factors, http://linkedlifedata.com/resource/pubmed/keyword/HOUSING, http://linkedlifedata.com/resource/pubmed/keyword/Health, http://linkedlifedata.com/resource/pubmed/keyword/Health Education--women, http://linkedlifedata.com/resource/pubmed/keyword/Health Surveys--women, http://linkedlifedata.com/resource/pubmed/keyword/IMMUNITY, http://linkedlifedata.com/resource/pubmed/keyword/Immunologic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Infections, http://linkedlifedata.com/resource/pubmed/keyword/Physiology, http://linkedlifedata.com/resource/pubmed/keyword/Population, http://linkedlifedata.com/resource/pubmed/keyword/Population Characteristics, http://linkedlifedata.com/resource/pubmed/keyword/Reproductive Tract Infections, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/Research Report, http://linkedlifedata.com/resource/pubmed/keyword/Residence Characteristics, http://linkedlifedata.com/resource/pubmed/keyword/Risk Factors, http://linkedlifedata.com/resource/pubmed/keyword/Rural Population--women, http://linkedlifedata.com/resource/pubmed/keyword/Sexually Transmitted Diseases, http://linkedlifedata.com/resource/pubmed/keyword/Socioeconomic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Socioeconomic Status, http://linkedlifedata.com/resource/pubmed/keyword/Spatial Distribution, http://linkedlifedata.com/resource/pubmed/keyword/Studies, http://linkedlifedata.com/resource/pubmed/keyword/TANZANIA
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0300-5771
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-7
pubmed:dateRevised
2006-11-15
pubmed:otherAbstract
PIP: Ophthalmologists analyzed data on 205 women with ingrowing eyelashes caused by trachomatous scarring (trichiasis) with data on 410 age- and village-matched controls to determine risk factors for trichiasis in trachoma hyperendemic areas where women face a greater risk of trichiasis than do men. All women lived in the Kongwa subdistrict of Dodoma Region, Tanzania. Cases were 3.6 times more likely to have a mother who also had trichiasis. Family history of fathers or other relatives was not associated with trichiasis, however. Cases tended to have never married (odds ratio [OR] = 3.7), suggesting that in a society that expects marriage women with trichiasis were socially and economically marginalized. Mothers with trichiasis were more apt to experience at least 5 deaths of children than controls (OR = 2.6). The researchers assumed that a factor common to both trichiasis and increased child deaths (e.g., socioeconomic status) accounted for this association. Controls were more likely to have attended adult education classes than cases (OR = 2.2), yet attendance at primary school was not a predictor for trichiasis. Women who had slept in a room with a cooking fire during their reproductive years were more prone to trichiasis than women who did during childhood or as current practice (OR -1.8), indicating a more profound pathogenic response (scarring) to infection with Chlamydia trachomatis during pregnancy. Living in a wood/earth (i.e., traditional) home during childbearing years was also a significant predictor of trichiasis (OR = 2.1). These findings suggest that improving living conditions, educational opportunities, and socioeconomic status during the childbearing years would reduce the risk for trichiasis and blindness.
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Risk factors for trichiasis in women in Kongwa, Tanzania: a case-control study.
pubmed:affiliation
Helen Keller International, New York, NY.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't